Nicotinamide

Basic Information:

Synonyms: Niacinamide

CAS: 98-92-0

Molecular Formula: C₆H₆N₂O

Molecular Weight: 122.12

Properties: White powder; soluble in water.

ONE OF THE MOST IN-DEMAND INGREDIENTS IN COSMETICS

One of the biggest appeals of Nicotinamide is its long list of benefits.

Nicotinamide works with skin's natural chemistry to improve overall skin texture by rebuilding a ipid layer, minimizing the appearance of pores, and preventing UV/ damage and infiammation as an antioxidant. It can also help with discoloration and redness, diminish fine lines and wrinkles by boosting collagen, and it's a good choice for those with sensitive skin, rosacea, and acne.

Nicotinamide is also effective when paired with other ingredients because it can help to strengthen the skin barier, thus making other ingredients easier to tolerate.

Effect:

① Prevention and treatment of pellagra, stomatitis, glossitis, etc

② Nutritional enhancer that promotes digestion

③ Blocking melanin transport and brightening the skin

Applications:

① Nutritional enhancement

② Feed additive

③ Whitening ingredient in cosmetics

Skin Lightening Effect:

Nicotinamide is an effective skin lightening compound that works by inhibiting melanosome transfer from melanocytes to keratinocytes.

Table 2. Skin-lightening efficacy of cosmeceuticals containing nicotinamide

Boo, Y.C. Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation. Antioxidants 2021, 10, 1315.

Greatens A, Hakozaki T, Koshoffer A, Epstein H, Schwemberger S, Babcock G, Bissett D, Takiwaki H, Arase S, Wickett RR, Boissy RE. Effective inhibition of melanosome transfer to keratinocytes by lectins and niacinamide is reversible. Exp Dermatol 2005: 14: 498 – 508. # Blackwell Munksgaard, 2005

Anti-Aging:

Nicotinamide is a precursor for co-factors NAD(H) and NADP(H) that are important in a variety of cellular pathways that affect skin physiology. NAD(H) and NADP(H) decrease with age giving rise to the notion that supplementing skin with niacinamide can provide anti-aging benefits. In their reduced forms, NADH and NADPH act as antioxidants that can mitigate oxidative stress associated with intrinsic aging and photoaging.

Why Choose Viablife Nicotinamide:

Nicotinic Acid can cause vasodilation and redness to skin.

Viablife's patented technology "Biotransformation method for heterocyclic transfering to amide" can make the Nicotinic Acid Residual in Nicotinamide<10 on the market.