Ascorbyl Tetraisopalmitate for Skincare Formulations

Product Overview

Ascorbyl Tetraisopalmitate (CAS No.: 183476-82-6) is a premium oil-soluble Vitamin C derivative widely recognized as one of the most advanced forms of stabilized Vitamin C used in modern cosmetic and personal care formulations. Also known as VCIP (Vitamin C Tetraisopalmitate), this next-generation active ingredient combines exceptional oxidative stability, superior skin affinity, and outstanding transdermal absorption, making it a preferred choice for high-performance skincare products.

Unlike traditional water-soluble Vitamin C, which is often limited by instability and poor skin penetration, Ascorbyl Tetraisopalmitate is specifically engineered to overcome these challenges. Its lipid-compatible molecular structure allows it to penetrate deeply into the skin barrier, delivering Vitamin C benefits more efficiently while maintaining long-term formulation stability.

As a benchmark ingredient in premium skincare development, VCIP is widely used in brightening, anti-aging, antioxidant, and skin-repair formulations by leading international cosmetic brands.

Product Specifications

Product Name: Ascorbyl Tetraisopalmitate
CAS No.: 183476-82-6
INCI Name: Ascorbyl Tetraisopalmitate
Molecular Formula: C70H128O10
Molecular Weight: 1129.76
Appearance: Colorless to pale yellow transparent liquid
Purity: ≥98%
Odor: Characteristic odor
Specific Gravity: 0.92–0.96
Refractive Index: 1.440–1.480
Packaging: 25 kg/drum

Key Features of Ascorbyl Tetraisopalmitate

Exceptional Stability
One of the most important advantages of Ascorbyl Tetraisopalmitate is its superior chemical stability. Compared with traditional ascorbic acid, it shows significantly improved resistance to oxidation, discoloration, and degradation during manufacturing, storage, and long-term product use.

Oil-Soluble Technology
As a lipid-soluble Vitamin C derivative, it integrates easily into oil-based systems, anhydrous formulations, and emulsions, providing greater flexibility for cosmetic formulators.

Superior Skin Penetration
Known as the “king of transdermal absorption,” VCIP penetrates the skin barrier more effectively than conventional Vitamin C derivatives, enabling deeper delivery and enhanced performance.

Excellent Skin Compatibility
Its mild, non-irritating nature makes it suitable for sensitive skin formulations and supports broader application across multiple skin types.

Cosmetic Benefits and Skin Performance

Brightening and Whitening
Ascorbyl Tetraisopalmitate helps visibly improve dull skin by inhibiting tyrosinase activity, reducing melanin formation, and promoting a more even skin tone. It is highly effective in brightening formulations targeting dark spots and pigmentation concerns.

Powerful Antioxidant Protection
It helps neutralize free radicals generated by UV exposure, pollution, and environmental stress, supporting healthier-looking skin and preventing premature aging.

Anti-Aging Support
By stimulating collagen synthesis, Ascorbyl Tetraisopalmitate helps improve skin elasticity, reduce the appearance of fine lines, and support firmer, younger-looking skin.

Anti-Inflammatory and Skin Repair
Its soothing properties help calm irritated skin, support acne recovery, and strengthen the skin barrier.

Suitable Skin Types

Due to its gentle and highly compatible nature, Ascorbyl Tetraisopalmitate is suitable for a wide range of skin types, including:

• dry skin;

• sensitive skin;

• mature skin;

• oily skin;

• pigmented skin;

• combination skin.

Its non-comedogenic profile also makes it suitable for acne-prone skincare formulations.

Recommended Formulation Applications

Because of its excellent oil solubility and formulation versatility, Ascorbyl Tetraisopalmitate is widely used in:

• facial oils and oil-based serums;

• anti-aging creams and lotions;

• brightening emulsions;

• sunscreens and after-sun care;

• lip care products;

• makeup primers and foundations;

• luxury skincare concentrates.

Its stability allows brands to create high-performance formulations without the common discoloration issues associated with traditional Vitamin C.

Formulation Guidelines

To maximize ingredient performance, the following formulation recommendations are advised:

Recommended pH Range
Optimal stability is achieved below pH 6.0. With suitable antioxidants and chelating agents, systems may remain stable up to pH 7.0.

Addition Method
Add directly into the oil phase during formulation. Avoid prolonged exposure to temperatures above 80°C.

Compatibility Recommendations
For enhanced antioxidant synergy, combine with:

• Vitamin E (Tocopherol);

• Squalane;

• Linoleic Acid;

• Ceramides;

• Natural plant oils.

These combinations can improve both efficacy and formulation stability.

Why Choose SACH BIOTECH

SACH BIOTECH is committed to delivering premium cosmetic active ingredients for global skincare manufacturers and brands. Our Ascorbyl Tetraisopalmitate is produced under strict quality standards to ensure:

• consistent high purity;

• reliable global supply;

• excellent batch-to-batch stability;

• strong technical support;

• trusted performance in premium cosmetic applications.

With growing demand for advanced oil-soluble Vitamin C ingredients, SACH BIOTECH Ascorbyl Tetraisopalmitate provides the quality and innovation needed for next-generation skincare development.